Research Studies
Completed Research Studies
The Impacts of Yi Ren Qigong on Self-Care
Funded by the Institute of Qigong & Internal Alternative Medicine
Principal Investigator: Guan-Cheng Sun, PhD
Project Period: 2009 – 2010
The purpose of this project is to investigate the impacts of a specific style of Qigong, Yi Ren, on the practitioner's health and well-being. This will be achieved with a self-report questionnaire form.
Integrating CAM: Nursing Emphasis (UW collaboration, Bastyr subcontractor)
Principal Investigator: M Heitkemper, Co-Investigator: T Callahan
Project Period: 2002 – 2009
The primary purpose was to enhance the integration of information about CAM therapies into UW health sciences curricula, specifically the required undergraduate nursing didactic and clinical courses, and by increasing the nursing faculty's understanding of CAM.
Graduate Certificate in CAM: An Integrative Approach
Principal Investigator: Sandra Motzer (UW), Co-Investigator: Timothy C. Callahan
Project Period: 2006 – 2009
This grant provided advanced practice nurses, graduate nursing students, and other health professionals opportunities to expand their understanding of complementary and alternative practices all within the context of culturally competent and cost effective care, ultimately, improving patient care.
Effects of Qigong, Tai Chi and Yoga Practice on Indicators of Health and Quality of Life in Older Adults
Funded by Gencare Incorporated
Principal Investigator: Mark Martzen
Project Period: 2008 – 2009
This study was conducted at Gencare Incorporated resident facilities in the Pacific Northwest looking at the effects of different activities on the quality of life in seniors.
Testing Oral Glutathione Supplementation in Healthy Adults
Principal Investigator: Jason Allen, ND, MPH
Project Period: 2008 – 2009
This randomized, placebo-controlled trial was conducted to determine the effect of oral GSH supplementation on systemic markers of oxidative stress (F2-isoprostanes, 8-hydroxy-2'-deoxyguanosine (8-OHdG)), in healthy adult volunteers (N=40), as well as changes in red blood.
Will a Naturopathic Diet Improve Glycemic Management?
Principal Investigator: EB Oberg
Project Period: 2008 – 2009
This pilot trial tests the feasibility and effectiveness of the naturopathic diet as it compares to standard conventional dietary education. Preliminary data will be used to determine if a naturopathic diet improves glycemic control, quality of life, and nutritional knowledge outcomes.
A Randomized Trial of CAM at the End of Life (UW collaboration, Bastyr subcontractor)
Principal Investigator: B Lafferty (UW), Co-Investigator: L J Standish
Project Period: September 2003 - 2008
The objective is to improve the quality of patient dying and death by the use of integrative medicine using mind, body, and energy interventions to complement allopathic comfort care for persons with advanced cancer and AIDS. The effects of the study will be measured by the assessment of functional status, symptoms, and post-death evaluation of the quality of dying and death.
Trametes versicolor in Women with Breast Cancer
Principal Investigator: L.J. Standish
Project Period: February 2005 - 2007
This is a Phase II randomized-placebo controlled trial of a mushroom extract (Trametes versicolor or Tv) in women with early-stage estrogen receptor-negative and progesterone receptor-negative breast cancer who have completed adjuvant radiation therapy. The primary study endpoint is immune recovery as measured by changes in natural killer cell activity. The secondary endpoints include phagocytic activity, cytokine levels (TNF-alpha and interferon-gamma), and self-reported quality of life/fatigue scores using previously validated instruments. This data will help the investigators to determine if Tv extract has promise as an immune therapy, and/or whether it might be helpful to fight fatigue in women after they finish conventional breast cancer treatment.
Effectiveness of Two Levels of Pulse Consumption on Caloric Restriction Adherence and Chronic Disease Risk, Pulse Canada Innovation Project
Principal Investigator: Megan McCrory
Project Period: September 1, 2006 - March 31, 2008
Pulses (dried beans, peas, lentils, and chickpeas) are example foods that are high in fiber, complex carbohydrates and protein, and low in caloric density. They may aid in weight loss and help prevent regain. This proposal will test whether regular pulse consumption can assist with weight loss and its maintenance, as well as promote improvement in risk for chronic disease using a randomized controlled study design.
Trametes versicolor-inducted Immunopotentiation
Principal Investigator: Cynthia Wenner, PhD
Project Period: October 2005 - August 2010
This diversity supplement project is designed to provide research training to Lisa Price ND, under mentorship of Cynthia Wenner, PhD. Dr. Price is studying the modulatory effects of Trametes versicolor on T helper 1 and T helper 2 phenotypic expression in healthy individuals as a substudy that is integral to the first aim of the parent Project 2 that is part of the Developmental Center for Research on CAM.
Eating Patterns and Metabolism Study
Principal Investigator: M McCrory
Project Period: 2004 – 2007
This clinical study is looking at the effects of foods and nutrients on metabolism and eating patterns.
Controlled Trial of an Herbal Treatment for Attention Deficit Hyperactivity Disorder
Principal Investigator: W Weber
Project Period: April 1, 2002 - March 31, 2007
A two-year study of 58 participants is planned. This study will test to see if there are benefits for juveniles (6-17) who take the herbal treatment to treat ADHD. Each participant and a parent or guardian will have study visits over a 9-week period. The safety of this herbal treatment will also be examined by tracking adverse events experienced by participants.
Menopause Effects on Obesity, Energy Balance & Insulin (Pennington Biomedical Research Center collaboration, Bastyr subcontractor)
Principal Investigator: S Smith (Pennington), Co-Investigator: J Lovejoy
Project Period: September 2003 - 2007
This observational study examines changes in body composition, energy intake and physical activity in a cohort of 160 perimenopausal women. Annual assessments will be conducted for 7 years to determine the impact of changing reproductive hormone concentrations on body fatness, fat distribution, energy balance and insulin resistance.
Synergy in Immunomodulation by Spilanthes and Echinacea (UNC-Greensboro collaboration, Bastyr subcontractor)
Principal Investigator: N Cech, Co-Investigator: C Wenner
Project Period: August 15, 2003 - July 31, 2006
The aims of this project are to determine which constituents of Spilanthes acmella and Echinacea purpurea have immunomodulatory activity and to assess the importance of synergy in the combined immunomodulatory activity of the two extracts.
Introducing a CAM Curriculum at the UW School of Medicine (UW collaboration, Bastyr subcontractor)
Principal Investigator: R Schneeweiss, Co-Investigator: T Callahan
Project Period: September 2001 - June 2006
The goal is to prepare allopathic medical students to communicate more effectively with patients about CAM practices and to broaden allopathic students’ knowledge about herbals, supplements and drug-herb interactions. The aims are to develop and integrate an interdisciplinary evidence-based CAM curriculum in the medical school program at UW-SOM and design and implement faculty development in CAM for clinical faculty.
K01 Mentored Research Scientist Development Award: Composition, Activity and Drug Interactions of Echinacea
Principal Investigator: Cynthia Wenner
Project Period: September 2000 - July 2006
The aims of this research project are to assess how Echinacea composition correlates with immunological activities, determine the role of cytochrome P450 metabolism in bioactivity of reportedly active constituents, and investigate whether distinct constituents synergize to enhance bioactivity of complex Echinacea extracts.
The Naturopathic Medical Research Agenda
Principal Investigator: Leanna Standish, PhD
Project Dates: 2003-2005
This project was designed to bring together naturopathic physicians and conventional research scientists to establish the Naturopathic Medical Research Agenda workgroup. It highlights the use of a prioritization criteria to determine the specific focus of future research efforts.
Telehealth Delivery of a Weight Loss Program in Diabetes
Principal Investigator: J Lovejoy
Project Period: September 2003 - August 2005
Aims: to transfer internet-based weight loss program on the Healthium platform, conduct focus groups for consumer acceptability and convenience of the interface, and to perform a pilot study in Type 2 Diabetes patients to determine whether the Healthium interface is improving weight loss.
Phase I/II Randomized Open-Label Dose-Finding Study of IdB 1016 in Hepatitis C (UW collaboration, Bastyr subcontractor)
Principal Investigator: C Krowdley, Co-Investigator: L J Standish
Project Period: June 1, 2002 - April 30, 2004
The aim of this study is to gather evidence for dose-dependent safety and tolerability of an oral silybinphosphatidylcholine phystosome (Siliphos TM) at three doses in subjects with chronic hepatitis C with stages II, III, and IV of liver fibrosis. Effects will be measured by certain changes that occur during the 12-week treatment and the 4-week follow-up. This study will determine an optimal dose based on measured safety, tolerability and therapeutic effects for a future phase II randomized double blind, placebo-controlled clinical trial.
Insurance Financing of CAM (UW subcontractor)
Principal Investigator: B Lafferty, Co-Investigator: L J Standish
Project Period: September 1, 2001 - September 30, 2004
Anti-HIV Activity of Botanical Preparations
Principal Investigator: C Wenner
Project Period: August 1, 2000 - December 31, 2003
Transfer of Neural Energy
Principal Investigator: L J Standish
Project Period: July 14, 2000 - June 24, 2003
Distant Healing Therapy in HIV/AIDS (California Pacific Medical Center Research Institute subcontractor)
Principal Investigator: E Targ, D Abrams, Co-Investigator: L J Standish
Project Period: July 1, 2000 - April 30, 2003
Alternative Medical Care Outcomes in AIDS (AMCOA)
Principal Investigator: L J Standish
Project Period: May 8, 2000 - March 31, 2003
Echinacea for Upper Respiratory Infection (URI) in Pediatrics , (UW subcontractor)
Principal Investigator: J Taylor, Co-Investigator: L J Standish
Project Period: April 1, 2000 - March 31, 2002
An Appreciative Inquiry Approach to Public Health Activities at Northwest Indian College and Bastyr University: Strengthening Northwest Indian Education and Career Ladders in Public Health
Principal Investigator: Henry Ziegler, MD, MPH
Project Period: December 1, 2000 - December 1, 2001
Evaluating Clinical Services at the Bastyr Center for Natural Health
Principal Investigator: J Guiltinan, ND
Project Period: October 10, 2000 - September 24, 2001
Use of Alternative Medicine by Cancer Patients: SEER Special Studies ( Fred Hutchinson Cancer Research Center subcontractor)
Principal Investigator: Patterson R, M Neuhauser, S Schwartz, Co-Investigator: L J Standish, PhD, ND, MS, LAc
Project Period: July 1, 1998 - June 30, 1999
Multi-Center AIDS Cohort Study (MACS)
Principal Investigator: L J Standish
Project Period: December 1, 1994 - September 28, 1999
Homeopathic Combination in the Treatment of Subjective Tinnitus: A Double-blind Crossover Trial
Principal Investigator: L J Standish
Project Period: January 22, 1998 - January 26, 1999
The Influence of Echinacea on Phagocytosis in Human Neutrophils and Monocytes in an Ex Vivo Model
Principal Investigator: C Calabrese
Project Completed 1998
Topical Bercidin vs. Standard Treatment to Heal Wounds or Non-Healing Ulcers in the Nursing Home Population
Principal Investigators: Rafael Gonzales-Vizoso MD, and Carlos Calabrese, ND, MPH
Project Period: October 28, 1997 - October 27, 1998
Study of the Effect of Medium Chain Triglycerides on Serum Triglycerides
Principal Investigator: C Calabrese
Project Period: September 1, 1995 - October 1, 1996
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