Ou Zhang, MD, PhD

Current Roles

  • Core faculty member: Department of Basic Sciences
  • School of Naturopathic Medicine
  • Bastyr university San Diego


  • MD, Xiangya School of Medicine, Central South University, China     
  • PhD, Texas Tech University                                
  • Postdoctoral Research Fellow, University of Michigan Medical School

Teaching/Research Interest

Microbiology, Lipid metabolism of Leishmania, Molecular pathogenesis of Toxoplasma gondii

Teaching/healing philosophy

I believe a teacher should always be passionate and have a heart for helping others. For the students, a good teacher should act as an external source to foster the intrinsic motivation to learn.

Classes Taught

Immunology, Infectious Diseases, Anatomy and Physiology, Fundamentals of Research Design

Past Professional Experiences

  • Postdoctoral Research Fellow, University of Michigan Medical School
  • Member of American Heart Association

 Books or Articles Authored

  • Bullen HE, Jia Y, Yamaryo-Botté Y, Bisio H, Zhang O, Jemelin NK, Marq JB, Carruthers VB, Botté CY, Soldati-Favre D. Phosphatidic Acid-Mediated Signaling Regulates Microneme Secretion in Toxoplasma. (2016) Cell Host Microbe. 2016 Mar 9;19(3):349-60.
  • Zhang, O., et al. (2013) Sphingosine kinase A is a pleiotropic and essentialenzyme for Leishmania survival and virulence. Mol. Microbiol. 2013 Nov;90(3):489-501. doi: 10.1111/mmi.12378.
  • Zhang, O., et al. (2012) Developmentally Regulated Sphingolipid Degradation in Leishmania major. PLoS ONE. 2012;7(1):e31059. PMCID: 3267774.
  • Pillai, A. B., Xu, W., Zhang, O., and Zhang, K. (2012) Sphingolipid Degradation in Leishmania (Leishmania)amazonensis. PLoS Negl Trop Dis. 2012 Dec;6(12):e1944. PMCID: 3527339. 
  • Zhang, O., et al. (2009) Degradation of Host Sphingomyelin Is Essential for Leishmania Virulence. PLoS Pathog 5(12): e1000692. doi:10.1371/journal.ppat.1000692.
  • Guerra AJ, Zhang O, Bahr C, Huynh M, DelProposto J, Brown WC, Wawrzak Z, Koropatkin N, Carruthers VB. (2018) Structure basis of Toxoplasma gondii Perforin-Like Protein 1 membrane interaction and activity during egress (PLoS Pathogen, submitted).

Professional Affiliations

  • Member, Texas Tech University Association of Biologist
  • Member, American Heart Association


American Heart Association (AHA) Postdoctoral Fellowship



Headshot of Ou Zhang

Ou Zhang, MD, PhD

Ou Zhang, MD, PhD